Extracellular Vesicle Marker Changes Associated With Disease Activity in Relapsing-Remitting Multiple Sclerosis
We speculate that the higher release of EVs containing CD29, CD31, CD40, CD44, CD49c, and CD69 in plasma, at low levels of circulating NfL/GFAP, may be associated with reduced immune cell activity in RRMS. These EV markers may characterize patients with RRMS in disease stabilization.
Authors
- Kirsten Guse
- Vincent Pernet (ORCID: https://orcid.org/0000-0002-9618-972X)
- Andrew Lung-Tat Chan (ORCID: https://orcid.org/0000-0003-3434-7283)
- Maria‐Eleftheria Evangelopoulos (ORCID: https://orcid.org/0000-0003-4654-7477)
- Jens Kühle (ORCID: https://orcid.org/0000-0002-6963-8892)
- Stefanie Marti (ORCID: https://orcid.org/0000-0001-8237-6965)
- Nicole Mueller‐Wirth
- Victoria Lim Falk
- Dimitris Karathanasis (ORCID: https://orcid.org/0000-0001-8070-6043)
- Aleksandra Maleska Maceski (ORCID: https://orcid.org/0000-0002-1916-5927)
- Amar Zadic
- Cornelia Schlup
Institutions
- University of Bern (CH)
- University of Basel (CH)
- University Hospital of Bern (CH)
- University Hospital of Basel (CH)
- Eginition Hospital (GR)
- Université Laval (CA)
- CSL (Switzerland) (CH)
Publication Details
- Journal
- Neurology Neuroimmunology & Neuroinflammation
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1212/nxi.0000000000200404
- Citations
- 4
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 3.22