Mechanism of lncRNA gadd7 regulating mitofusin 1 expression by recruiting LSD1 to down-regulate H3K9me3 level, and mediating mitophagy in alveolar type II epithelial cell apoptosis in hyperoxia-induced acute lung injury
LncRNA gadd7 regulated MFN1 expression by recruiting LSD1 to down-regulate H3K9me3 level and mediate mitophagy, thereby promoting AEC II apoptosis in HALI.
Authors
- Yingcong Ren
- Cunzhi Yin
- Hang Wu
- Miao Chen (ORCID: https://orcid.org/0000-0001-9560-6934)
- Xuan Xiao (ORCID: https://orcid.org/0000-0002-2184-6502)
- Jun Liu (ORCID: https://orcid.org/0000-0002-2454-4518)
- Guoyue Liu (ORCID: https://orcid.org/0000-0003-2963-0922)
- Guiyang Jia
Institutions
- Zunyi Medical University (CN)
Publication Details
- Journal
- Cell Biology and Toxicology
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1007/s10565-025-10021-x
- Citations
- 8
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 7.49
Funders
- National Natural Science Foundation of China
- Science and Technology Program of Guizhou Province