Anti-integrin αvβ6 autoantibody in patients with ulcerative colitis after proctocolectomy: a cross-sectional study in Japan
Serum anti-integrin αvβ6 antibody levels remain elevated in patients with UC even after total colectomy, and were significantly higher in patients with pouchitis than in those without. This antibody could be a novel and useful biomarker for the diagnosis of pouchitis and assessment of disease activity.
Authors
- Masaki Ominami (ORCID: https://orcid.org/0000-0002-9692-0420)
- Yuji Nadatani (ORCID: https://orcid.org/0000-0001-7081-8746)
- Tsuyoshi Yanagida (ORCID: https://orcid.org/0009-0007-2646-737X)
- Shusei Fukunaga (ORCID: https://orcid.org/0000-0002-9336-8271)
- Rieko Nakata (ORCID: https://orcid.org/0000-0001-9977-7239)
- Hirotsugu Maruyama (ORCID: https://orcid.org/0000-0002-8728-8101)
- Koji Otani (ORCID: https://orcid.org/0000-0001-9075-6415)
- Shuhei Hosomi (ORCID: https://orcid.org/0000-0002-8808-5672)
- Yumie Kobayashi (ORCID: https://orcid.org/0000-0002-5747-6697)
- Fumio Tanaka (ORCID: https://orcid.org/0000-0002-9186-1249)
- Yasuhiro Fujiwara (ORCID: https://orcid.org/0000-0002-1225-1785)
- Yu Nishida (ORCID: https://orcid.org/0000-0003-3369-5059)
Institutions
- Osaka Metropolitan University (JP)
- Tokyo Metropolitan University (JP)
Publication Details
- Journal
- Intestinal Research
- Published
- 2025-04-29
- DOI
- https://doi.org/10.5217/ir.2024.00170
- Citations
- 1
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 1.82