Quantitative assessment of biomechanical changes in oral lesions at different cancerous stages using optical coherence elastography
The ability of the shaker-OCE system to obtain the structural and biomechanical characteristics of tongue tissues in a non-invasive, real-time manner was confirmed by this study. It also showed notable benefits in terms of early diagnosis and the dynamic monitoring of tongue cancer. The systematic validation of the physiopathological model revealed a strong correlation between the elastic properties of cancerous tissues and pathological evolution, which provides a theoretical basis and experimental evidence for the clinical application of OCE technology.
Authors
- Yuhao Yang (ORCID: https://orcid.org/0009-0009-3208-9226)
- Xinyu Yang (ORCID: https://orcid.org/0000-0001-5498-1877)
- Wenqi Xiong (ORCID: https://orcid.org/0000-0003-2786-4493)
- Xiaojing Hu
- Hao Luo (ORCID: https://orcid.org/0000-0001-5181-7529)
- Zekun Li (ORCID: https://orcid.org/0000-0003-1763-7190)
- Wei‐Hua Chen (ORCID: https://orcid.org/0000-0003-2168-6147)
- Mei‐Tzu C. Tang (ORCID: https://orcid.org/0000-0001-8185-6609)
- Xingdao He (ORCID: https://orcid.org/0000-0002-3068-9131)
- Jian Yang (ORCID: https://orcid.org/0000-0002-0684-9772)
Institutions
- Nanchang University (CN)
- Education Department of Jiangxi Province (CN)
- Nanchang Hangkong University (CN)
Publication Details
- Journal
- Quantitative Imaging in Medicine and Surgery
- Published
- 2025-04-30
- DOI
- https://doi.org/10.21037/qims-24-2359
- Citations
- 3
- Primary Topic
- Proteoglycans and glycosaminoglycans research
- Type
- article
- Field-Weighted Citation Impact
- 3.45