Schizophrenia genetic risk and labour market outcomes in the Finnish general population: Are schizophrenia-related traits penalised or rewarded?
Beyond its overall negative association with employment, SCZ<sub>PRS</sub> exhibits a non-linear relationship with income in cognitive-intensive occupations, where both low and high SCZ<sub>PRS</sub> appear to be penalised. This pattern became more pronounced post-2000, coinciding with rising income inequality and technological advancements, likely reshaping labour market demands. While effect sizes are substantial, compensatory factors may mitigate these outcomes. Greater awareness of these associations and individual differences in labour market experiences could contribute to a more inclusive society.
Authors
- Veikko Salomaa
- Markus Perola
- Johanna Liuhanen (ORCID: https://orcid.org/0000-0002-1153-1013)
- Katri Kantojärvi (ORCID: https://orcid.org/0000-0002-1294-0310)
- Tuija Jääskeläinen (ORCID: https://orcid.org/0000-0001-6263-2298)
- Sonja Sulkava (ORCID: https://orcid.org/0000-0002-6938-2620)
- Tiina Paunio
- Seppo Koskinen
- Aaro Hazak
Institutions
- University of Helsinki (FI)
- Helsinki University Hospital (FI)
- Finnish Institute for Health and Welfare (FI)
- Institute for Molecular Medicine Finland (FI)
- Hospital District of Helsinki and Uusimaa (FI)
Publication Details
- Journal
- Comprehensive Psychiatry
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1016/j.comppsych.2025.152600
- Citations
- 1
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.82