Efficacy of Current Therapeutic Interventions in Diabetic Wound Healing

Diabetic wounds are one of the major health issues for people suffering from diabetes. They often do not heal well. The normal healing process is slow or does not work right. These wounds pose a risk to both patients and health care providers. Numerous traditional methods, viz. growth factor administration, cell therapy, gene therapy, wound dressings, skin transplants, and others, are being used to promote wound healing in various types of wounds. Current research focuses on innovative wound dressings that contain biological agents to promote wound healing more quickly. Nano-therapeutics, 3D bioprinting approaches, and stem cell treatment for enhancing curative results with prominence on skin regeneration with negligible side effects are recent innovations in advanced wound care technologies. In this review, the advantages and disadvantages of several cutting-edge and novel approaches viz. cold plasma treatment therapy, extracellular matrix-based techniques, and platelet-rich plasma-based techniques to fostering high-quality wound healing as well as future developments and challenges with these new methods have been reviewed.