Randomized Controlled Trial of Atorvastatin in Acute Influenza in the Emergency Department
Atorvastatin administration in acute influenza appears safe. We did not find attenuation of IL-6 with atorvastatin. Patients receiving atorvastatin reported improvement in their clinical symptoms at a faster rate than those in the placebo group, particularly in patients presenting within 48 hours of symptom onset. This trial is registered at ClinicalTrials.gov, Identifier: NCT02056340.
Authors
- Maureen Chase (ORCID: https://orcid.org/0000-0003-2451-122X)
- Michael N. Cocchi (ORCID: https://orcid.org/0000-0002-5541-5209)
- Jacob Vine (ORCID: https://orcid.org/0000-0001-5254-2694)
- Anne V. Grossestreuer (ORCID: https://orcid.org/0000-0001-7316-5576)
- Ari L. Moskowitz (ORCID: https://orcid.org/0000-0002-0194-990X)
- Xiaowen Liu (ORCID: https://orcid.org/0000-0002-2543-4599)
- Michael W. Donnino
Institutions
- Beth Israel Deaconess Medical Center (US)
- Montefiore Medical Center (US)
Publication Details
- Journal
- Western Journal of Emergency Medicine
- Published
- 2025-04-29
- DOI
- https://doi.org/10.5811/westjem.33580
- Citations
- 2
- Primary Topic
- Vitamin C and Antioxidants Research
- Type
- article
- Field-Weighted Citation Impact
- 2.24