Comparison of TyG and modified TyG indices in predicting coronary slow flow phenomenon
Most of the demographic and clinical risk factors between CSFP patients and non-CSFP patients were comparable. For patients with CSFP, the patients were more likely to have chronic kidney disease (CKD) (39.13% vs. 20.31%, p < 0.001) and less likely to have anti-diabetic therapy (14.49% vs. 27.13%, p = 0.023). The patients with CSFP also had higher body weight index (BMI) (p < 0.001), higher levels of uric acid (UA), triglyceride (TG) (p = 0.017), total cholesterol (TC) (p = 0.016) and low-density lipoprotein cholesterol (LDL-C) (p = 0.006), homocysteine (p < 0.001) and uric acid (p < 0.002). Both TyG and its modified indices, including TyG-WC, TyG-BMI were demonstrated to be independently associated with CSFP in multi-variable logistic analysis after adjusting other co-variables.Further receiver operating characteristic (ROC) curve demonstrated that TyG-WC showed the best performance in predicting CSFP compared with other indices. Subgroup analysis revealed that the predictive value of TyG-WC in CSFP was consistent in different subgroups except that the predictive value was better in male patients compared with female patients, CONCLUSIONS: Our investigation reveals that TyG, TyG-WC and TyG-BMI were independent risk factors for CSFP. TyG-WC showed a better predictive performance than other indices in predicting CSFP.
Authors
- Lijun Han (ORCID: https://orcid.org/0009-0007-1524-412X)
- Xingsheng Yang
- Hongyu Hu
- Shuai Meng (ORCID: https://orcid.org/0000-0003-4196-6496)
- Wei Chen (ORCID: https://orcid.org/0000-0003-0903-7945)
- Jing Nan
- Zening Jin
- Ruofei Jia
Institutions
- Capital Medical University (CN)
- Beijing Tian Tan Hospital (CN)
Publication Details
- Journal
- BMC Cardiovascular Disorders
- Published
- 2025-04-30
- DOI
- https://doi.org/10.1186/s12872-025-04794-6
- Citations
- 2
- Primary Topic
- Cardiac Imaging and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 2.72