Dorsal Root Ganglion Stimulation in Patients With Refractory Abdominal Pain: A Case Series

This case series highlights the use of dorsal root ganglion (DRG) stimulation for refractory chronic abdominal pain in three patients who failed to respond to conventional therapies. DRG stimulation modulates pain signals by targeting the sensory neurons present in the DRG. The three cases involved patients with chronic abdominal pain resulting from pancreatitis, endometriosis, and pancreatic cancer. DRG stimulation resulted in pain reductions of 100%, 90%, and 80%, respectively, accompanied by significant improvements in daily functionality and reduced analgesic use. These findings underscore the potential of DRG stimulation as a targeted, effective treatment for refractory abdominal pain. Further research with larger cohorts is warranted to validate these results and refine treatment protocols.

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Publication Details

Journal
Cureus
Published
2025-04-29
DOI
https://doi.org/10.7759/cureus.83218
Primary Topic
Pain Management and Treatment
Type
article
Field-Weighted Citation Impact
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article

Dorsal Root Ganglion Stimulation in Patients With Refractory Abdominal Pain: A Case Series

Geoffrey D. Panjeton, Hess Panjeton, Iqbal Khan, Zeshan R Ali et al.
Cureus
Pain Management and Treatment
article

Dorsal Root Ganglion Stimulation in Patients With Refractory Abdominal Pain: A Case Series

Geoffrey D. Panjeton, Hess Panjeton, Iqbal Khan, Zeshan R Ali, Beker Karadaghy
article en

Abstract

This case series highlights the use of dorsal root ganglion (DRG) stimulation for refractory chronic abdominal pain in three patients who failed to respond to conventional therapies. DRG stimulation modulates pain signals by targeting the sensory neurons present in the DRG. The three cases involved patients with chronic abdominal pain resulting from pancreatitis, endometriosis, and pancreatic cancer. DRG stimulation resulted in pain reductions of 100%, 90%, and 80%, respectively, accompanied by significant improvements in daily functionality and reduced analgesic use. These findings underscore the potential of DRG stimulation as a targeted, effective treatment for refractory abdominal pain. Further research with larger cohorts is warranted to validate these results and refine treatment protocols.

CureusVol. 17(4)
Washington University in St. Louis (US)
Openalex Percentile: Top 84%
Pain Management and Treatment
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