Conservative surgical management of large bilateral mandibular odontogenic keratocyst: a case report and literature review

Odontogenic keratocyst (OKC) have a been a controversial topic within the medical, research and taxonomy community. It is because of these controversies this requires our special attention. From a clinician’s view, its varied presentation and high recurrence rate makes it special. One possible explanation for such high recurrence is the presence of anti-apoptotic gene; BCL-2 in high concentration in the epithelial lining of OKCs. Even rarer is its presentation bilaterally, we present one such case of a young male. After facing multiple misdiagnosis and any significant improvement, he was finally diagnosed on the basis of biopsy and underwent serial marsupialization followed by enucleation. We present this case to stress on the fact that conservative surgical management by marsupialization under local anaesthesia itself is enough without the need of costly reconstruction in cases with unilocular cyst involving the mandible bilaterally with review of relevant literature.

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Publication Details

Journal
International Journal of Research in Medical Sciences
Published
2025-04-29
DOI
https://doi.org/10.18203/2320-6012.ijrms20251337
Primary Topic
Oral and Maxillofacial Pathology
Type
article
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article

Conservative surgical management of large bilateral mandibular odontogenic keratocyst: a case report and literature review

Sujeet Kumar Singh, Kavita Garg, Satendar Tulsi, Praveen Kumar Pandey et al.
International Journal of Research in Medical Sciences
Oral and Maxillofacial Pathology
article

Conservative surgical management of large bilateral mandibular odontogenic keratocyst: a case report and literature review

Sujeet Kumar Singh, Kavita Garg, Satendar Tulsi, Praveen Kumar Pandey, Shalvi Singh
article en

Abstract

Odontogenic keratocyst (OKC) have a been a controversial topic within the medical, research and taxonomy community. It is because of these controversies this requires our special attention. From a clinician’s view, its varied presentation and high recurrence rate makes it special. One possible explanation for such high recurrence is the presence of anti-apoptotic gene; BCL-2 in high concentration in the epithelial lining of OKCs. Even rarer is its presentation bilaterally, we present one such case of a young male. After facing multiple misdiagnosis and any significant improvement, he was finally diagnosed on the basis of biopsy and underwent serial marsupialization followed by enucleation. We present this case to stress on the fact that conservative surgical management by marsupialization under local anaesthesia itself is enough without the need of costly reconstruction in cases with unilocular cyst involving the mandible bilaterally with review of relevant literature.

International Journal of Research in Medical SciencesVol. 13(5)
Malabar Medical College Hospital and Research Centre (IN)
Openalex Percentile: Top 88%
Oral and Maxillofacial Pathology
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