The Impact of High Temperature Stress on the Immune System and Mitigation of Nutrients

Heat waves have become a widespread environmental concern worldwide and have had a serious impact on human health. Among them, the impact of high temperature on the immune system has become one of the focus of global attention. High temperature and heat wave can reduce the antioxidant performance of living organisms, produce heat stress, damage the immunoreactivity, intestinal histomorphology and microbiota, and aggravate autoimmune diseases. Nutrients such as resveratrol may strengthen the immune response and prevent disease, thus alleviating or reversing the immune damage caused by high temperature. This review summarizes the effects of high temperature on the biological immune system and the latest findings of nutrients that alleviate this phenomenon, to provide a theoretical basis for the development of effective nutritional intervention strategies and provide new ideas for the prevention of biological immune damage by high temperature and heat wave.