Complexities Surrounding N-1-Methylpseudouridine (M1ψ) in COVID-19 Synthetic Gene Therapies

N-1-methylpseudouridine (m1Ψ) was introduced into modified-mRNA vaccines to reduce immunogenicity and increase mRNA stability, but its presence can indeed affect translation in several ways.

Authors

Publication Details

Journal
Journal of Independent Medicine
Published
2025-04-29
DOI
https://doi.org/10.71189/jim/2025/v01n02a11
Primary Topic
Virus-based gene therapy research
Type
article
Field-Weighted Citation Impact
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article

Complexities Surrounding N-1-Methylpseudouridine (M1ψ) in COVID-19 Synthetic Gene Therapies

Abdul Mannan Baig, Andrew Zywiec
Journal of Independent Medicine
Virus-based gene therapy research
article

Complexities Surrounding N-1-Methylpseudouridine (M1ψ) in COVID-19 Synthetic Gene Therapies

Abdul Mannan Baig, Andrew Zywiec
article en

Abstract

N-1-methylpseudouridine (m1Ψ) was introduced into modified-mRNA vaccines to reduce immunogenicity and increase mRNA stability, but its presence can indeed affect translation in several ways.

Journal of Independent MedicineVol. 01(02)
Openalex Percentile: Top 89%
Virus-based gene therapy research
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Complexities Surrounding N-1-Methylpseudouridine (M1ψ) in COVID-19 Synthetic Gene Therapies — Abdul Mannan Baig, Andrew Zywiec · Journal of Independent Medicine (2025) | TGRS Research Map | TGRS