Real-World Experience Using Proton Versus Photon Craniospinal Irradiation for Leptomeningeal Disease
In a single-institutional experience treating LMD, acute cytopenias likely caused by CSI were not different between proton and photon CSI across all major cell lines. Survival was also similar between modalities; therefore, photon CSI may be a safe, efficacious option for LMD.
Authors
- Uğur Sener (ORCID: https://orcid.org/0000-0002-3919-7408)
- Thomas B. Bradley
- Alain Meyer (ORCID: https://orcid.org/0000-0003-0893-6041)
- Lauren M. Webb (ORCID: https://orcid.org/0000-0002-4937-6848)
- Anita Mahajan (ORCID: https://orcid.org/0000-0003-4260-7022)
- David M. Routman (ORCID: https://orcid.org/0000-0002-2768-003X)
- William S. Harmsen (ORCID: https://orcid.org/0000-0001-7134-5362)
- K.M. Frechette
- Elizabeth Yan
- Paul D. Brown (ORCID: https://orcid.org/0000-0003-0022-4533)
- Nadia N. Laack (ORCID: https://orcid.org/0000-0002-4385-6349)
- Eric J. Lehrer (ORCID: https://orcid.org/0000-0002-1216-6230)
- William G. Breen (ORCID: https://orcid.org/0000-0001-8039-2398)
- Sydney Pulsipher
- Roman O. Kowalchuk
- Witold Matysiak
- Sara B Leier
Institutions
- Mayo Clinic (US)
- Mayo Clinic in Arizona (US)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- Practical Radiation Oncology
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1016/j.prro.2025.03.015
- Citations
- 3
- Primary Topic
- Brain Metastases and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.56