Nasopharyngeal necrosis following intensity-modulated radiation therapy of primary nasopharyngeal carcinoma—incidence rate and predictors of risk
This real-world study provided valuable information for prevention of PRNN. Compared with RTOG protocol, D<sub>0.5cc</sub><sup>EQD2</sup> > 80.20 Gy is a reliable evidence-based new complement to dose constraint, especially for T3-4 disease, who received high prescribe dose in China.
Authors
- Li Lin (ORCID: https://orcid.org/0000-0003-1052-1566)
- Xue-Cen Wang
- Jia Kou (ORCID: https://orcid.org/0009-0005-6296-5507)
- Dan‐Wan Wen
- Yong Chen (ORCID: https://orcid.org/0000-0002-3891-2721)
- Sha-Sha He
- Xing-Li Yang
- Yan Wang (ORCID: https://orcid.org/0000-0002-1743-6383)
Institutions
- Sun Yat-sen University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Sun Yat-sen University Cancer Center (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1186/s12885-025-14086-z
- Citations
- 1
- Primary Topic
- Oral health in cancer treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- National Natural Science Foundation of China