Clinical manifestations of SARS-CoV-2 Omicron infection is associated with the stage of liver cirrhosis
SARS-CoV-2 omicron variants caused a more severe inflammatory response in cirrhotic patients than in non-cirrhotic patients, but no further deterioration of liver function. Instead, patients with advanced stage of liver cirrhosis showed milder respiratory symptoms and pulmonary lesions. These results underscore the intricate relationship between Omicron infection and cirrhosis, highlighting the necessity for personalized clinical approaches in managing this specific patient group.
Authors
- Fengjiao Wang (ORCID: https://orcid.org/0009-0007-5347-8875)
- Lingxiao Zhu (ORCID: https://orcid.org/0000-0003-4148-4307)
- Lanjuan Li
- Yanfei Chen (ORCID: https://orcid.org/0000-0002-2185-9303)
Institutions
- National Clinical Research Center for Digestive Diseases (CN)
- Jinan Stomatological Hospital (CN)
- Shandong First Medical University (CN)
- State Key Laboratory of Diagnosis and Treatment of Infectious Diseases
- Zhejiang University (CN)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1186/s12879-025-11040-z
- Citations
- 1
- Primary Topic
- COVID-19 Clinical Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China