Síndrome de Steven Johnson en un paciente de 14 años por consumo de Lamotrigina. Reporte de caso

Stevens-Johnson Syndrome (SJS) is a serious adverse drug reaction characterized by high mortality and lack of effective treatments. This study presents a clinical case of a 14-year-old male patient who developed SJS after administration of lamotrigine. The patient presented erythema, blisters, and mucosal involvement, which led to hospitalization. A multidisciplinary management was implemented, including drug discontinuation, administration of corticosteroids and immunoglobulin, which led to a favorable recovery. The literature review demonstrated variations in the clinical presentation and management of SJS, highlighting the importance of close monitoring in the use of lamotrigine, especially in pediatric patients, to prevent severe adverse reactions. This case illustrates the need for rigorous protocols and preventive strategies in public health.

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Publication Details

Journal
Gaceta Médica de la Junta de Beneficencia de Guayaquil
Published
2025-04-29
DOI
https://doi.org/10.61708/nxf7w764
Primary Topic
Drug-Induced Adverse Reactions
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article
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article

Síndrome de Steven Johnson en un paciente de 14 años por consumo de Lamotrigina. Reporte de caso

María Isabel Sánchez Dávila, C Castro, Ma. Fernanda Jaime Barrezueta
Gaceta Médica de la Junta de Beneficencia de Guayaquil
Drug-Induced Adverse Reactions
article

Síndrome de Steven Johnson en un paciente de 14 años por consumo de Lamotrigina. Reporte de caso

María Isabel Sánchez Dávila, C Castro, Ma. Fernanda Jaime Barrezueta
article en

Abstract

Stevens-Johnson Syndrome (SJS) is a serious adverse drug reaction characterized by high mortality and lack of effective treatments. This study presents a clinical case of a 14-year-old male patient who developed SJS after administration of lamotrigine. The patient presented erythema, blisters, and mucosal involvement, which led to hospitalization. A multidisciplinary management was implemented, including drug discontinuation, administration of corticosteroids and immunoglobulin, which led to a favorable recovery. The literature review demonstrated variations in the clinical presentation and management of SJS, highlighting the importance of close monitoring in the use of lamotrigine, especially in pediatric patients, to prevent severe adverse reactions. This case illustrates the need for rigorous protocols and preventive strategies in public health.

Gaceta Médica de la Junta de Beneficencia de GuayaquilVol. 3(1)
Hospital Pedro de Elizalde (AR), Universidad Católica de Santiago de Guayaquil (EC)
Openalex Percentile: Top 89%
Drug-Induced Adverse Reactions
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Síndrome de Steven Johnson en un paciente de 14 años por consumo de Lamotrigina. Reporte de caso — María Isabel Sánchez Dávila, C Castro, et al. · Gaceta Médica de la Junta de Beneficencia de Guayaquil (2025) | TGRS Research Map | TGRS