Low-dose hormonal intrauterine contraception: New options

The article presents an analysis of the literature data on the modern possibilities of hormonal intrauterine contraceptive systems. Intrauterine systems (IUDs) are one of the most effective, safe and acceptable methods of contraception. According to statistics, about 1/3 of the female population of Russia, 1/2 – women of East Asia use IUD as contraception, which is most likely due to the lack of opportunity and desire for constant monitoring of the use of contraceptives (pills, patch, intravaginal ring). In a number of studies conducted in the last 10 years, there has been a more than threefold increase in the frequency of IUD use in women aged 15–24 years. Until recently, hormonal IUDs (Mirena) were usually used in women who gave birth, but the development of a new IUD, Kailin, containing 19.5 mg of levonorgestrel, is actively used in more than 30 countries around the world as a highly effective and acceptable method of contraception with a low content of LNG. Many studies have been conducted to investigate the effectiveness, acceptability and safety of IUD. Thus, in one of the largest prospective observational multicenter KYSS study, satisfaction with the use of IUD LNG was assessed for one year. The study included 1,114 women. The results of the study showed: satisfaction with this method of contraception in 86.1% of women, the desire to continue using Kailina – 81.4%, as well as a low percentage (16.9%) of adverse events. Therefore, IUD-LNG IUD is an effective, acceptable, safe method of contraception that allows to prevent the onset of unwanted pregnancy, including in young unborn women.