Repeat Resection for Recurrent Glioblastoma in the WHO 2021 Era: A Longitudinal Matched Case-Control Study
Complete repeat resection may improve overall survival in patients with recurrent IDH-wildtype GBM and should be considered earlier as a therapeutic option rather than a diagnostic or salvage procedure. Early surgical intervention, before declines in the KPS and GCS or tumor volumes become unmanageable, may lead to better outcomes. Further studies with larger cohorts are needed to confirm these findings.
Authors
- David Schiff
- Cengiz S. Askun
- Figen Söylemezoğlu (ORCID: https://orcid.org/0000-0002-8002-5165)
- Aynur Azizova (ORCID: https://orcid.org/0000-0002-9354-2612)
- Hatice Yağmur Zengin (ORCID: https://orcid.org/0000-0002-9855-2449)
- Melike Mut (ORCID: https://orcid.org/0000-0002-9601-9907)
Institutions
- Middle East Technical University (TR)
- University of Virginia (US)
- Hacettepe University (TR)
- Vrije Universiteit Amsterdam (NL)
Publication Details
- Journal
- Brain Sciences
- Published
- 2025-04-27
- DOI
- https://doi.org/10.3390/brainsci15050463
- Citations
- 2
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.25