ANTIBIOTIC USE IN THE TREATMENT OF URINARY TRACT INFECTION AT TRUNG VUONG HOSPITAL

Introduction: Urinary tract infection (UTI) is a common infectious disease. Inappropriate use of antibiotics in the treatment of UTIs can reduce treatment effectiveness and increase antibiotic resistance. Objectives: To investigate clinical and laboratory characteristics, antibiotic use pattern, and to identify factors associated with the length of hospital stay in the treatment of UTIs at Trung Vuong Hospital. Methods: A cross - sectional study was conducted on medical records of inpatients with UTIs (01/06/2022-31/05/2023) treated at the Department of Nephrology - Urology, Trung Vuong Hospital. The appropriateness of antibiotic use was evaluated using current guidelines. Logistic regression was used to determine factors related to the length of hospital stay. Results: A total of 213 medical records of UTI inpatients were included (male accounted for 55.4%). Mean age was 52.9 ± 14.5, with 79.3% of patients <65 years old. A great proportion of patients experienced common clinical symptoms, including flank pain and dysuria (75.6% and 43.7% respectively). There were 66.2% of patients with ≥25 leukocytes/µL urine. The most dominant bacteria isolated was Escherichia coli. The most common antibiotics used were β-lactams and fluoroquinolones (93.4% and 33.8%, respectively). Empiric antibiotics were properly indicated in 50.7% of patients. Age and surgical interventions were associated with prolonged hospital stays (p<0.05). Conclusions: The majority of patients exhibited common symptoms of UTI, and elevated urine leukocytes. The appropriateness of antibiotic use was suboptimal. Patients aged ³65, undergoing surgical interventions were more likely to have longer hospital stays.