Hemidiaphragm work in large pleural effusion and its insignificant impact on blood gases: a new insight based on in silico study
Our findings emphasize the significance of mediastinal compliance in pleural effusion physiology and suggest insignificant influence of the ipsilateral hemidiaphragm inverted due to large PE on arterial gas tensions. This study underscores the utility of virtual patient models for elucidating unexpected physiological behaviors and optimizing clinical interventions.
Authors
- Elżbieta M. Grabczak (ORCID: https://orcid.org/0000-0003-0901-118X)
- Rafał Krenke (ORCID: https://orcid.org/0000-0002-0087-2031)
- Tomasz Gólczewski (ORCID: https://orcid.org/0000-0001-8228-6775)
- Monika Zielińska-Krawczyk
- Anna M. Stecka (ORCID: https://orcid.org/0000-0003-4912-3776)
- Marcin Michnikowski (ORCID: https://orcid.org/0000-0003-3218-6906)
Institutions
- Medical University of Warsaw (PL)
- Institute of Biocybernetics and Biomedical Engineering (PL)
- Polish Academy of Sciences (PL)
Publication Details
- Journal
- Frontiers in Physiology
- Published
- 2025-04-11
- DOI
- https://doi.org/10.3389/fphys.2025.1539781
- Citations
- 1
- Primary Topic
- Pleural and Pulmonary Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.52