In Silico Prioritization of STAT1 3′ UTR SNPs Identifies rs190542524 as a miRNA-Linked Variant with Potential Oncogenic Impact

These analyses suggest that these 3' UTR SNPs may have a functional impact on the STAT1 gene's regulation through their predicted effect on miRNA binding sites. Future experimental validation could establish their potential role in the diagnosis and treatment of various diseases, including cancer.

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Publication Details

Journal
Non-Coding RNA
Published
2025-04-29
DOI
https://doi.org/10.3390/ncrna11030032
Citations
5
Primary Topic
Cancer-related molecular mechanisms research
Type
article
Field-Weighted Citation Impact
4.68

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article

In Silico Prioritization of STAT1 3′ UTR SNPs Identifies rs190542524 as a miRNA-Linked Variant with Potential Oncogenic Impact

Ebtihal Kamal
5 citations
Non-Coding RNA
Cancer-related molecular mechanisms research
4.68
article

In Silico Prioritization of STAT1 3′ UTR SNPs Identifies rs190542524 as a miRNA-Linked Variant with Potential Oncogenic Impact

Ebtihal Kamal
article en
5 citations

Abstract

These analyses suggest that these 3' UTR SNPs may have a functional impact on the STAT1 gene's regulation through their predicted effect on miRNA binding sites. Future experimental validation could establish their potential role in the diagnosis and treatment of various diseases, including cancer.

Non-Coding RNAVol. 11(3)
Prince Sattam Bin Abdulaziz University (SA)
Prince Sattam bin Abdulaziz University
Openalex Percentile: Top 5%
Cancer-related molecular mechanisms research
4.68
DOIOpen Access PDFOpenAlex
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In Silico Prioritization of STAT1 3′ UTR SNPs Identifies rs190542524 as a miRNA-Linked Variant with Potential Oncogenic Impact — Ebtihal Kamal · Non-Coding RNA (2025) | TGRS Research Map | TGRS