Individually designed ablation of low-voltage areas in persistent atrial fibrillation—a randomized controlled trial (IDEAL-AF): study design and rationale
IDEAL-AF is a multi-centre, randomized, controlled clinical trial investigating whether ablation of LVZs in addition to PVI reduces the recurrence rate of atrial arrhythmias and improves HRQoL compared to PVI-only in patients with persistent AF and LVZs. This study has the potential to modify recommendations regarding ablation techniques for this specific patient cohort.
Authors
- Niklas Höglund (ORCID: https://orcid.org/0009-0008-2585-5327)
- Astrid Paul‐Nordin (ORCID: https://orcid.org/0000-0001-6431-8358)
- Finn Åkerström (ORCID: https://orcid.org/0000-0003-0611-8416)
- Emmanouil Charitakis (ORCID: https://orcid.org/0000-0002-2514-5324)
- Nikola Drca (ORCID: https://orcid.org/0000-0001-9158-4942)
- Jari Tapanainen (ORCID: https://orcid.org/0000-0001-7718-1602)
- Mats Jensen‐Urstad (ORCID: https://orcid.org/0000-0002-2727-3493)
- Henrik Almroth (ORCID: https://orcid.org/0000-0003-2618-5966)
- Csaba Herczku
Institutions
- Linköping University (SE)
- Karolinska University Hospital (SE)
- Sahlgrenska University Hospital (SE)
- Danderyds sjukhus (SE)
- Karolinska Institutet (SE)
- University Hospital of Umeå (SE)
- Linköping University Hospital (SE)
Publication Details
- Journal
- European Heart Journal Open
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1093/ehjopen/oeaf037
- Citations
- 3
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 4.16
Funders
- Vetenskapsrådet
- Center for Innovative Medicine