Allogenic Bioengineered Cartilage Achieves Hyaline Cartilage Repair in a Large Animal Model: A Promising Step Forward
This successful preclinical study highlights allogenic cartilage beads as a promising method for cartilage repair. Moreover, using donor chondrocytes may allow reduced patient morbidity and 1-step surgery. Hence, this advanced therapy medicinal product is suitable for treating large lesions and older patients and is currently being evaluated in a phase I/IIa clinical trial.
Authors
- Sana Boudabbous (ORCID: https://orcid.org/0000-0003-0516-4613)
- Vannary Tieng (ORCID: https://orcid.org/0000-0001-6463-3139)
- Jacques Ménétrey (ORCID: https://orcid.org/0000-0002-3925-8784)
- Philippe M. Tscholl (ORCID: https://orcid.org/0000-0003-1702-7114)
- Halah Kutaish (ORCID: https://orcid.org/0000-0001-5016-4466)
- Vincent Braunersreuther
- Laura Bengtsson
- François Lazeyras (ORCID: https://orcid.org/0000-0002-9364-0634)
- Sébastien Courvoisier (ORCID: https://orcid.org/0000-0001-9309-4154)
- Didier Hannouche (ORCID: https://orcid.org/0000-0003-2060-2394)
- Sabine E. Hammer (ORCID: https://orcid.org/0000-0003-1475-3938)
Institutions
- University of Veterinary Medicine Vienna (AT)
- University Hospital of Geneva (CH)
- Hirslanden Clinique La Colline (CH)
- Centre d'Imagerie BioMedicale (CH)
- University of Lausanne (CH)
Publication Details
- Journal
- The American Journal of Sports Medicine
- Published
- 2025-04-27
- DOI
- https://doi.org/10.1177/03635465251331224
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00