Impact of Foot Surgery and Pharmacological Treatments on Functionality and Pain in Rheumatoid Arthritis: A Five-Year Longitudinal Study
Patients with long-standing RA on non-biologic therapy exhibited the greatest decline in foot function, whereas early treatment with MTX (<10 years of disease duration) appeared to slow deterioration. Surgery did not consistently provide functional benefits, and biologics helped mitigate progression, though outcomes varied. These findings underscore the importance of early intervention and personalized treatment strategies for foot preservation in RA.
Authors
- Alejandro Castillo-Domínguez (ORCID: https://orcid.org/0000-0001-8524-1847)
- Laura Ramos‐Petersen (ORCID: https://orcid.org/0000-0002-9349-7751)
- Andrés Reinoso‐Cobo (ORCID: https://orcid.org/0000-0002-1185-2941)
- María José Pérez-Galán
- Ana Belén Ortega‐Ávila (ORCID: https://orcid.org/0000-0001-5738-5691)
- Gabriel Gijón-Noguerón (ORCID: https://orcid.org/0000-0003-4558-3548)
- Amparo Campos-Cano
Institutions
- Hospital Universitario Virgen de las Nieves (ES)
- Instituto de Investigación Biomédica de Málaga (ES)
- Universidad de Málaga (ES)
Publication Details
- Journal
- Healthcare
- Published
- 2025-04-27
- DOI
- https://doi.org/10.3390/healthcare13091004
- Citations
- 1
- Primary Topic
- Rheumatoid Arthritis Research and Therapies
- Type
- article
- Field-Weighted Citation Impact
- 1.67