Reassessing the Prognostic Value of Lymph Node Metastasis in Deficient Mismatch Repair Colorectal Cancer
LOODS was identified as a more effective independent prognostic factor compared with traditional pN staging, enabling more precise stratification of pN+ patients in non-metastatic dMMR CRC, highlighting its potential utility in guiding postoperative treatment and optimizing therapeutic strategies.
Authors
- Zezhi Shan
- Dakui Luo (ORCID: https://orcid.org/0000-0003-1648-5930)
- Zilan Ye
- Junyong Weng (ORCID: https://orcid.org/0000-0003-1826-3952)
- Fan Chen (ORCID: https://orcid.org/0000-0002-5739-2776)
- Jiayu Chen (ORCID: https://orcid.org/0000-0003-3353-938X)
- Qingguo Li (ORCID: https://orcid.org/0000-0002-4658-2152)
- Liang Yu (ORCID: https://orcid.org/0009-0007-3922-3454)
- Xinxiang Li
Institutions
- Shanghai Medical College of Fudan University (CN)
- Fudan University Shanghai Cancer Center (CN)
Publication Details
- Journal
- Current Oncology
- Published
- 2025-04-27
- DOI
- https://doi.org/10.3390/curroncol32050254
- Primary Topic
- Genetic factors in colorectal cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Fudan University