Easy-to-Apply Hydrogel Patch for Field Treatment and Monitoring of Equine Wounds

The cicatrization process, which is critical to equine health, directly affects overall well-being by preventing infection, minimizing tissue damage, and restoring optimal function. Herein, we present a case of a 5-year-old sorrel mare with a torn skin wound on the dorsal aspect of the metatarsal region of the left hind limb, treated locally with an antibiotic-free transparent hydrogel-based patch while monitoring its healing process. The patch induced pink granulation tissue in the treated area after 42 days, while keloid formation was observed in the untreated area. Wound measurements showed a reduction over time with patch treatment, with complete healing achieved at 116 days. Capillary formation and a velvety appearance were observed on day 80. Histological analysis revealed mature granulation tissue, fibrocyte formation, abundant capillaries, organized collagen fibrils, and development of type III collagen in the treated area. Interestingly, no inflammatory response was observed during treatment. The hydrogel patch not only accelerated healing, but also controlled excessive granulation tissue formation. This treatment represents an innovative approach to equine wound management that updates applications for owners while reducing costs.

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Publication Details

Journal
Gels
Published
2025-04-27
DOI
https://doi.org/10.3390/gels11050328
Primary Topic
Wound Healing and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Easy-to-Apply Hydrogel Patch for Field Treatment and Monitoring of Equine Wounds

Silvia Romanini, Sol R. Martínez, Patricia Bertone, María Emilia Zambroni et al.
Gels
Wound Healing and Treatments
article

Easy-to-Apply Hydrogel Patch for Field Treatment and Monitoring of Equine Wounds

Silvia Romanini, Sol R. Martínez, Patricia Bertone, María Emilia Zambroni, Ana Lucía Cabral, Marı́a L. Gómez, Andrés S. Boatti
article en

Abstract

The cicatrization process, which is critical to equine health, directly affects overall well-being by preventing infection, minimizing tissue damage, and restoring optimal function. Herein, we present a case of a 5-year-old sorrel mare with a torn skin wound on the dorsal aspect of the metatarsal region of the left hind limb, treated locally with an antibiotic-free transparent hydrogel-based patch while monitoring its healing process. The patch induced pink granulation tissue in the treated area after 42 days, while keloid formation was observed in the untreated area. Wound measurements showed a reduction over time with patch treatment, with complete healing achieved at 116 days. Capillary formation and a velvety appearance were observed on day 80. Histological analysis revealed mature granulation tissue, fibrocyte formation, abundant capillaries, organized collagen fibrils, and development of type III collagen in the treated area. Interestingly, no inflammatory response was observed during treatment. The hydrogel patch not only accelerated healing, but also controlled excessive granulation tissue formation. This treatment represents an innovative approach to equine wound management that updates applications for owners while reducing costs.

GelsVol. 11(5)
Consejo Nacional de Investigaciones Científicas y Técnicas (AR), Universidad Nacional de Río Cuarto (AR)
Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad Nacional de Río Cuarto, Agencia Nacional de Promoción Científica y Tecnológica
Openalex Percentile: Top 88%
Wound Healing and Treatments
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