A Case of Long-Term Survival in Feline Esophageal Squamous Cell Carcinoma Treated with Endoscopic Resection and Toceranib combined with Meloxicam.

A 12-year-old spayed female cat was presented with a 3-month history of anorexia, dysphagia, weight loss, vomiting, and regurgitation. Computed tomography and endoscopy revealed a neoplastic lesion obstructing the esophageal lumen and cauliflower-like masses adjacent to the heart. Histopathology confirmed squamous cell carcinoma. The cat underwent endoscopic tumor debulking and chemotherapy with toceranib (7.5mg/cat, p.o., EOD or thrice weekly) combined with meloxicam (0.17-0.35mg/kg, p.o., SID). After 67 days, the neoplastic lesions had regressed significantly, and by the 190th day, the cat remained healthy. Balloon dilation was performed several times due to esophageal stricture.

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Publication Details

Journal
Journal of Japan Veterinary Cancer Society
Published
2025-04-28
DOI
https://doi.org/10.12951/jvcs.2024-002
Primary Topic
Cancer Research and Treatments
Type
article
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article

A Case of Long-Term Survival in Feline Esophageal Squamous Cell Carcinoma Treated with Endoscopic Resection and Toceranib combined with Meloxicam.

Yoshitsugu Mitani, Yukai Murata, Yoshiaki Hashimoto, Katsuhiro Gamou
Journal of Japan Veterinary Cancer Society
Cancer Research and Treatments
article

A Case of Long-Term Survival in Feline Esophageal Squamous Cell Carcinoma Treated with Endoscopic Resection and Toceranib combined with Meloxicam.

Yoshitsugu Mitani, Yukai Murata, Yoshiaki Hashimoto, Katsuhiro Gamou
article en

Abstract

A 12-year-old spayed female cat was presented with a 3-month history of anorexia, dysphagia, weight loss, vomiting, and regurgitation. Computed tomography and endoscopy revealed a neoplastic lesion obstructing the esophageal lumen and cauliflower-like masses adjacent to the heart. Histopathology confirmed squamous cell carcinoma. The cat underwent endoscopic tumor debulking and chemotherapy with toceranib (7.5mg/cat, p.o., EOD or thrice weekly) combined with meloxicam (0.17-0.35mg/kg, p.o., SID). After 67 days, the neoplastic lesions had regressed significantly, and by the 190th day, the cat remained healthy. Balloon dilation was performed several times due to esophageal stricture.

Journal of Japan Veterinary Cancer SocietyVol. 14(2)
The Schwarzman Animal Medical Center (US)
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Openalex Percentile: Top 89%
Cancer Research and Treatments
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