A Case of Long-Term Survival in Feline Esophageal Squamous Cell Carcinoma Treated with Endoscopic Resection and Toceranib combined with Meloxicam.
A 12-year-old spayed female cat was presented with a 3-month history of anorexia, dysphagia, weight loss, vomiting, and regurgitation. Computed tomography and endoscopy revealed a neoplastic lesion obstructing the esophageal lumen and cauliflower-like masses adjacent to the heart. Histopathology confirmed squamous cell carcinoma. The cat underwent endoscopic tumor debulking and chemotherapy with toceranib (7.5mg/cat, p.o., EOD or thrice weekly) combined with meloxicam (0.17-0.35mg/kg, p.o., SID). After 67 days, the neoplastic lesions had regressed significantly, and by the 190th day, the cat remained healthy. Balloon dilation was performed several times due to esophageal stricture.
Authors
- Yoshitsugu Mitani (ORCID: https://orcid.org/0000-0002-8661-4702)
- Yukai Murata
- Yoshiaki Hashimoto (ORCID: https://orcid.org/0000-0002-6696-5011)
- Katsuhiro Gamou
Institutions
- The Schwarzman Animal Medical Center (US)
Publication Details
- Journal
- Journal of Japan Veterinary Cancer Society
- Published
- 2025-04-28
- DOI
- https://doi.org/10.12951/jvcs.2024-002
- Primary Topic
- Cancer Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00