Demystifying Prolonged Antibiotic Use for Blood Culture-negative Sepsis Evaluations in the Neonatal Intensive Care Unit
Although it is challenging to limit the initiation of antibiotics in infants with complex underlying disease processes with concern for sepsis, minimizing antibiotic use can be achieved by timely discontinuation when cultures are negative. A robust antimicrobial stewardship program can identify valid reasons for prolonged antibiotic administration and suggest approaches to minimize antibiotic exposure.
Authors
- Robert W. Grundmeier (ORCID: https://orcid.org/0000-0002-8290-5588)
- Mary Catherine Harris (ORCID: https://orcid.org/0000-0001-6287-0026)
- Lakshmi Srinivasan (ORCID: https://orcid.org/0000-0002-6786-9523)
- Nithya Sivakumar (ORCID: https://orcid.org/0009-0001-5451-7174)
Institutions
- Children's Hospital of Philadelphia (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- The Pediatric Infectious Disease Journal
- Published
- 2025-04-28
- DOI
- https://doi.org/10.1097/inf.0000000000004836
- Citations
- 2
- Primary Topic
- Neonatal and Maternal Infections
- Type
- article
- Field-Weighted Citation Impact
- 3.76