Non-tuberculous mycobacterial lymphadenitis in an infant with Hyper IgM Syndrome: A rare case report
Hyper Immunoglobulin M syndrome is rare. We report a 7-month-old infant who suffered Hyper Immunoglobulin M syndrome and developed non-tuberculous mycobacterial (NTM) lymphadenitis. The former was confirmed by next-generation sequencing revealed X-linked recessive, whilst initial immunoglobulin testing displayed high IgM levels. The latter was diagnosed by lymph node pus acid-fast staining smear, culture and PCR. The child received therapy. Meanwhile, he was treated with immune supporting. The child was followed up for 11 months, and he progressed well.
Authors
- Yemin Lan (ORCID: https://orcid.org/0000-0003-3455-3618)
- Lili Luo
- Weiwen Li (ORCID: https://orcid.org/0000-0003-3545-6430)
- Xiayan Meng
- Chaoyan Xu
- Chunyan Zhao (ORCID: https://orcid.org/0009-0001-7071-1962)
- Ai-Chun Huang
- Qingdong Zhu (ORCID: https://orcid.org/0009-0003-3368-5296)
- Chang Song
- Xianzhen Huang
- Shaoyong Xi
Institutions
- The Fourth People's Hospital (CN)
- The Second Nanning People's Hospital (CN)
Publication Details
- Journal
- Diagnostic Microbiology and Infectious Disease
- Published
- 2025-04-28
- DOI
- https://doi.org/10.1016/j.diagmicrobio.2025.116871
- Primary Topic
- Mycobacterium research and diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Guangxi Zhuang Region Health Department