Mechanical stress facilitates calcium influx and growth of alveolar epithelial cells via activation of the BDKRB1/Ca2+/CaMKII/MEK1/ERK axis
Appropriate levels of mechanical stress contribute to the growth and calcium influx of alveolar epithelial cells by modulating BDKRB1/Ca<sup>2+</sup>/CaMKII/MEK1/ERK signaling.
Authors
- Rongshuang Yan (ORCID: https://orcid.org/0009-0005-2362-6430)
- Shixin Xu (ORCID: https://orcid.org/0000-0002-8207-7313)
- Derui Fei
- Ying Zhang (ORCID: https://orcid.org/0000-0002-5908-307X)
- Li Quan (ORCID: https://orcid.org/0000-0003-3930-4987)
- Cheng Pan (ORCID: https://orcid.org/0000-0002-8884-4405)
- Zhanjun Shi (ORCID: https://orcid.org/0000-0002-0005-3650)
- Yang Luo (ORCID: https://orcid.org/0000-0001-7477-4728)
- Qingdong Zhang (ORCID: https://orcid.org/0000-0001-9744-9960)
Institutions
- Kunming Medical University (CN)
Publication Details
- Journal
- Respiratory Research
- Published
- 2025-04-28
- DOI
- https://doi.org/10.1186/s12931-025-03240-7
- Citations
- 4
- Primary Topic
- Ion channel regulation and function
- Type
- article
- Field-Weighted Citation Impact
- 3.22
Funders
- National Natural Science Foundation of China
- Kunming Medical University
- Yunnan Provincial Science and Technology Department