Single-cell Resolved Oncogene Co-expression: From Principles to Clinical Impact
This commentary explores the concept and utility of studying oncogene co-expression at single-cell resolution and its clinical and biological implications. We emphasize the importance of scalable methods, mathematically driven quantification models, and artificial intelligence integration to enhance the clinical utility of this approach.
Authors
- Anand D. Jeyasekharan (ORCID: https://orcid.org/0000-0001-9816-6137)
- Shruti Sridhar (ORCID: https://orcid.org/0000-0002-0388-0352)
- Allison Chan (ORCID: https://orcid.org/0000-0001-5657-0270)
Institutions
- National University of Singapore (SG)
- National University Cancer Institute, Singapore (SG)
- National Cancer Centre Singapore (SG)
- National University Health System (SG)
Publication Details
- Journal
- Blood Cancer Discovery
- Published
- 2025-04-28
- DOI
- https://doi.org/10.1158/2643-3230.bcd-25-0064
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Medical Research Council
- National Medical Research Council