When Diabetic Ketoacidosis Reveals Pancreatic Cancer: A Case Report and Literature Review

Pancreatic adenocarcinoma is an aggressive cancer often diagnosed at a late stage. This article highlights an unusual presentation: diabetic ketoacidosis (DKA) as the initial manifestation. We present a clinical case illustrating this association and explore the pathophysiological mechanisms linking new-onset diabetes to pancreatic cancer. We emphasize the importance of a thorough evaluation in the face of unexplained DKA, particularly in patients with no prior history of diabetes, to detect potential pancreatic neoplasia early. The implications for diagnosis, therapeutic management, and research perspectives are discussed.

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Publication Details

Journal
Scholars Journal of Medical Case Reports
Published
2025-04-26
DOI
https://doi.org/10.36347/sjmcr.2025.v13i04.039
Primary Topic
Diet and metabolism studies
Type
article
Field-Weighted Citation Impact
0.00
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When Diabetic Ketoacidosis Reveals Pancreatic Cancer: A Case Report and Literature Review

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Diet and metabolism studies
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When Diabetic Ketoacidosis Reveals Pancreatic Cancer: A Case Report and Literature Review

Fetohi Mohammed, Aziz Bazine, Youssef Touimri, Toreis Mehdi, Talib Imad, Abdennour Rhanmi
article en

Abstract

Pancreatic adenocarcinoma is an aggressive cancer often diagnosed at a late stage. This article highlights an unusual presentation: diabetic ketoacidosis (DKA) as the initial manifestation. We present a clinical case illustrating this association and explore the pathophysiological mechanisms linking new-onset diabetes to pancreatic cancer. We emphasize the importance of a thorough evaluation in the face of unexplained DKA, particularly in patients with no prior history of diabetes, to detect potential pancreatic neoplasia early. The implications for diagnosis, therapeutic management, and research perspectives are discussed.

Scholars Journal of Medical Case ReportsVol. 13(04)
Openalex Percentile: Top 89%
Diet and metabolism studies
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