The features and risk factors of thrombotic thrombocytopenic purpura in systemic lupus erythematosus
SLE patients with higher SLEDAI-2K score, high baseline T-CHO levels, and renal involvement were predisposed to TTP development. The short-term mortality is increased for SLE-TTP patients of advanced age and in non-nulliparous females. Close monitoring and active treatments of these patients are needed for this life-threatening situation.
Authors
- Yingchao Yang (ORCID: https://orcid.org/0000-0002-1157-1744)
- Li‐Jun Huo (ORCID: https://orcid.org/0000-0002-9479-2218)
- Tian-Fang Li (ORCID: https://orcid.org/0000-0002-3039-8676)
- Yujie He
- Hang Ma (ORCID: https://orcid.org/0000-0001-7565-6889)
- Shanshan Li (ORCID: https://orcid.org/0000-0002-7646-3680)
Institutions
- China-Japan Friendship Hospital (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Orphanet Journal of Rare Diseases
- Published
- 2025-04-28
- DOI
- https://doi.org/10.1186/s13023-025-03741-0
- Primary Topic
- Complement system in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China