Causal effects of obesity on estimated glomerular filtration rate: a Mendelian randomization and image data analysis study
This study suggests a causal negative effect of obesity on cystatin C-based, but not creatinine-based eGFR. These findings warrant further research regarding estimations of kidney function when assessing obesity and CKD.
Authors
- Lars Lind (ORCID: https://orcid.org/0000-0003-2335-8542)
- Robin Strand (ORCID: https://orcid.org/0000-0001-7764-1787)
- Håkan Åhlström (ORCID: https://orcid.org/0000-0002-8701-969X)
- Maria K Eriksson Svensson (ORCID: https://orcid.org/0000-0001-7545-5585)
- Joel Kullberg (ORCID: https://orcid.org/0000-0001-8205-7569)
- Anders Olof Larsson (ORCID: https://orcid.org/0000-0003-3161-0402)
- Patrik Ene (ORCID: https://orcid.org/0009-0004-3763-0441)
Institutions
- Uppsala University (SE)
- Uppsala University Hospital (SE)
Publication Details
- Journal
- Clinical Kidney Journal
- Published
- 2025-04-25
- DOI
- https://doi.org/10.1093/ckj/sfaf116
- Citations
- 1
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- Akademiska Sjukhuset
- Stiftelsen Familjen Ernfors Fond
- Uppsala Universitet