Infective Endocarditis and Septic Emboli: Diagnostic Delays, Implications, and Challenges

Infective endocarditis (IE) presents significant diagnostic challenges and needs a high index of clinical suspicion. This study describes a case illustrating these complexities. A 69-year-old woman initially presented with confusion and expressive dysphasia, following five days of treatment for left-sided otitis media. Further investigations revealed evidence of Streptococcus infection. The patient was diagnosed with pneumococcal infective endocarditis, complicated by intracranial septic emboli and multiorgan failure. This resulted in prolonged hospital stay and the development of multi-morbidity and increased frailty index. IE was diagnosed only upon readmission, leading to delays in treatment. This study underscores the importance of early suspicion and repeat investigations in IE. Evolving diagnostic criteria emphasize a multidisciplinary approach to managing these life-threatening conditions.

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Publication Details

Journal
Cureus
Published
2025-04-28
DOI
https://doi.org/10.7759/cureus.83117
Citations
1
Primary Topic
Infective Endocarditis Diagnosis and Management
Type
article
Field-Weighted Citation Impact
1.35
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article

Infective Endocarditis and Septic Emboli: Diagnostic Delays, Implications, and Challenges

Ali Ibnian, JOHN CHINONYE AMADI, Maria Vincent
1 citations
Cureus
Infective Endocarditis Diagnosis and Management
1.35
article

Infective Endocarditis and Septic Emboli: Diagnostic Delays, Implications, and Challenges

Ali Ibnian, JOHN CHINONYE AMADI, Maria Vincent
article en
1 citations

Abstract

Infective endocarditis (IE) presents significant diagnostic challenges and needs a high index of clinical suspicion. This study describes a case illustrating these complexities. A 69-year-old woman initially presented with confusion and expressive dysphasia, following five days of treatment for left-sided otitis media. Further investigations revealed evidence of Streptococcus infection. The patient was diagnosed with pneumococcal infective endocarditis, complicated by intracranial septic emboli and multiorgan failure. This resulted in prolonged hospital stay and the development of multi-morbidity and increased frailty index. IE was diagnosed only upon readmission, leading to delays in treatment. This study underscores the importance of early suspicion and repeat investigations in IE. Evolving diagnostic criteria emphasize a multidisciplinary approach to managing these life-threatening conditions.

CureusVol. 17(4)
Milton Keynes Hospital NHS Foundation Trust (GB)
Zero hunger
Openalex Percentile: Top 21%
Infective Endocarditis Diagnosis and Management
1.35
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