Making a diagnosis of Alzheimer’s disease in asymptomatic individuals with positive biomarkers
About 25% of cognitively unimpaired older adults have an elevated brain amyloid burden comparable to that of individuals with symptomatic Alzheimer’s disease. Pomara and Imbimbo examine the ongoing debate over whether these individuals should be classified as having preclinical Alzheimer’s disease or simply be considered ‘at risk’.
Authors
- Nunzio Pomara (ORCID: https://orcid.org/0000-0003-2204-0102)
- Bruno Pietro Imbimbo (ORCID: https://orcid.org/0000-0002-0327-7262)
Institutions
- Nathan Kline Institute for Psychiatric Research (US)
- Chiesi Foundation (IT)
- New York University (US)
- Chiesi (France) (FR)
Publication Details
- Journal
- Brain
- Published
- 2025-04-28
- DOI
- https://doi.org/10.1093/brain/awaf162
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00