Evaluation of Ground and Aerial Ultra-Low Volume Applications Using ReMoa Tri Against Deltamethrin-Resistant Aedes aegypti from Collier County, Florida

New intervention methods and product formulations are needed to better control pyrethroid-resistant <i>Aedes aegypti</i> populations and mitigate the risk of mosquito-borne disease. ReMoa Tri is a novel adulticidal space spray that utilizes a different mode of action than the commonly used adulticides: pyrethroids and organophosphates. As a triple-action space spray, ReMoa Tri combines three components: Fenpropathrin, a mixed-type I/II pyrethroid; abamectin, a macrocyclic lactone; and C8910, a patented fatty acid chain. Prior studies performed by Collier Mosquito Control District showed that ReMoa Tri is effective at controlling type I pyrethroid-resistant <i>Ae. aegypti</i> mosquitoes. To further validate these results and the performance of ReMoa Tri, we conducted a semi-field evaluation using ground and aerial ULV (ultra-low volume) applications with field-caught deltamethrin-resistant <i>Ae. aegypti</i> and a susceptible <i>Ae. aegypti</i> laboratory strain. Ground evaluations tested ReMoa Tri and a type II pyrethroid-based product, DeltaGard. While ReMoa Tri was equally effective against Collier's deltamethrin-resistant <i>Ae. aegypti</i> and the susceptible laboratory strain, DeltaGard was effective against both strains, with reduced efficacy at farther distances. Similarly, aerial evaluations also showed that ReMoa Tri was equally effective against Collier's deltamethrin-resistant <i>Ae. aegypti</i> strain and susceptible laboratory strain. This study further confirms ReMoa Tri's potential as an effective alternative to pyrethroid-based adulticides, both in ground and aerial applications, for managing pyrethroid-resistant <i>Ae. aegypti</i>.