Rewiring of SINE-MIR enhancer topology and Esrrb modulation in expanded and naive pluripotency
Altogether, our study highlights the topological regulation of ESRRB on MIR in the naïve potency state.
Authors
- Jian Xu (ORCID: https://orcid.org/0000-0001-6194-6316)
- Reshma Taneja (ORCID: https://orcid.org/0000-0001-6214-6177)
- Joey Kay Hui Teo (ORCID: https://orcid.org/0000-0002-4987-8223)
- Florent Ginhoux (ORCID: https://orcid.org/0000-0002-2857-7755)
- Tushar Warrier (ORCID: https://orcid.org/0000-0003-4839-5067)
- Yingying Zeng (ORCID: https://orcid.org/0000-0002-4683-6060)
- Xuezhi Bi (ORCID: https://orcid.org/0000-0001-6702-0805)
- Yih‐Cherng Liou (ORCID: https://orcid.org/0000-0003-0149-6856)
- Derrick Sek Tong Ong (ORCID: https://orcid.org/0000-0001-7529-3790)
- Yuin‐Han Loh (ORCID: https://orcid.org/0000-0002-4715-6454)
- Zihao Zheng (ORCID: https://orcid.org/0009-0008-9113-6646)
- Jia Hao Jackie Teo
- Nadia Omega Cipta (ORCID: https://orcid.org/0009-0000-2270-9692)
- Yi Yao (ORCID: https://orcid.org/0000-0002-2116-4341)
- Yee Jiun Kok (ORCID: https://orcid.org/0000-0001-6875-8262)
- Hu Li (ORCID: https://orcid.org/0000-0001-5957-5472)
- Ka Wai Wong (ORCID: https://orcid.org/0000-0002-7869-0342)
Institutions
- Agency for Science, Technology and Research (SG)
- Mayo Clinic (US)
- Inserm (FR)
- National University of Singapore (SG)
- Nanyang Technological University (SG)
- Shanghai Jiao Tong University (CN)
- Université Paris-Saclay (FR)
- Singapore Immunology Network (SG)
- Institut Gustave Roussy (FR)
- SingHealth Duke-NUS Academic Medical Centre (SG)
- National University Cancer Institute, Singapore (SG)
- National Cancer Centre Singapore (SG)
- Bioprocessing Technology Institute (SG)
- Institute of Molecular and Cell Biology (SG)
Publication Details
- Journal
- Genome biology
- Published
- 2025-04-28
- DOI
- https://doi.org/10.1186/s13059-025-03577-8
- Citations
- 6
- Primary Topic
- Genetics and Neurodevelopmental Disorders
- Type
- article
- Field-Weighted Citation Impact
- 10.90
Funders
- Agency for Science, Technology and Research
- National Medical Research Council