Tuberculous meningitis initially presented with low levels of pleocytosis and protein in the cerebrospinal fluid: a case report

Tuberculous meningitis (TBM) is fatal unless treated promptly. Nonconvulsive status epilepticus (NCSE) may cause altered consciousness in patients with TBM. A 25-year-old female presented to the emergency department with a headache and fever along with multiple associated symptoms that had developed 2 days prior. Based on clinical findings, brain imaging, and cerebrospinal fluid (CSF) examination, she was tentatively diagnosed with viral meningitis. Later, she developed altered consciousness with focal seizures, and follow-up CSF examination findings and electroencephalography were consistent with NCSE complicated by TBM. We encountered a patient with TBM who exhibited initial atypical CSF findings and NCSE, and we report the case here and discuss the pathomechanisms.

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Publication Details

Journal
encephalitis
Published
2025-04-28
DOI
https://doi.org/10.47936/encephalitis.2025.00010
Primary Topic
Infectious Diseases and Tuberculosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Tuberculous meningitis initially presented with low levels of pleocytosis and protein in the cerebrospinal fluid: a case report

H. Jane Kim, Namoh Kim, Ilhan Yoo, Woong‐Woo Lee et al.
encephalitis
Infectious Diseases and Tuberculosis
article

Tuberculous meningitis initially presented with low levels of pleocytosis and protein in the cerebrospinal fluid: a case report

H. Jane Kim, Namoh Kim, Ilhan Yoo, Woong‐Woo Lee, Byung‐Kun Kim, Jungju Lee, Kyusik Kang
article en

Abstract

Tuberculous meningitis (TBM) is fatal unless treated promptly. Nonconvulsive status epilepticus (NCSE) may cause altered consciousness in patients with TBM. A 25-year-old female presented to the emergency department with a headache and fever along with multiple associated symptoms that had developed 2 days prior. Based on clinical findings, brain imaging, and cerebrospinal fluid (CSF) examination, she was tentatively diagnosed with viral meningitis. Later, she developed altered consciousness with focal seizures, and follow-up CSF examination findings and electroencephalography were consistent with NCSE complicated by TBM. We encountered a patient with TBM who exhibited initial atypical CSF findings and NCSE, and we report the case here and discuss the pathomechanisms.

encephalitisVol. 5(3)
Eulji University (KR)
Good health and well-being
Openalex Percentile: Top 85%
Infectious Diseases and Tuberculosis
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