Association of statin use on survival outcomes of patients with early-stage HER2-positive breast cancer in the APHINITY trial

In APHINITY, statin use was not associated with improved survival outcomes. These results must be interpreted with caution due to the exploratory nature of the analysis and the associated limitations.

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Publication Details

Journal
Breast Cancer Research and Treatment
Published
2025-04-28
DOI
https://doi.org/10.1007/s10549-025-07699-2
Citations
1
Primary Topic
Cancer, Lipids, and Metabolism
Type
article
Field-Weighted Citation Impact
0.94

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article

Association of statin use on survival outcomes of patients with early-stage HER2-positive breast cancer in the APHINITY trial

Christoph Thomssen, Mariana Brandão, Francesca Poggio, Noam Pondé et al.
1 citations
Breast Cancer Research and Treatment
Cancer, Lipids, and Metabolism
0.94
article

Association of statin use on survival outcomes of patients with early-stage HER2-positive breast cancer in the APHINITY trial

Christoph Thomssen, Mariana Brandão, Francesca Poggio, Noam Pondé, Rachel Schiff, Arlindo R. Ferreira, Richard D. Gelber, Carmine De Angelis, Susan Dent, Samuel Martel, Lieveke Ameye, Evandro de Azambuja, Elisa Agostinetto, Martine Piccart, Christian Maurer, Matteo Lambertini
article en
1 citations

Abstract

In APHINITY, statin use was not associated with improved survival outcomes. These results must be interpreted with caution due to the exploratory nature of the analysis and the associated limitations.

Breast Cancer Research and TreatmentVol. 212(1)
Université Libre de Bruxelles (BE), Université de Sherbrooke (CA), Daiichi Sankyo (Germany) (DE), Baylor College of Medicine (US), Heidelberg University (DE), Universidade Católica Portuguesa (PT), Institut Jules Bordet (BE), University Hospital Heidelberg (DE), Düsseldorf University Hospital (DE), Integrated Oncology (United States) (US), Daiichi Sankyo (United Kingdom) (GB), Hôpital Charles-Le Moyne (CA), National Center for Tumor Diseases (DE), Dana-Farber Cancer Institute (US), Dana-Farber/Harvard Cancer Center (US), Ospedale Policlinico San Martino (IT), University Hospital Cologne (DE), Daiichi Sankyo (United States) (US), Heinrich Heine University Düsseldorf (DE), University of Rochester (US), Martin Luther University Halle-Wittenberg (DE), University of Naples Federico II (IT), University of Genoa (IT)
F. Hoffmann-La Roche, Genentech
Good health and well-being
Openalex Percentile: Top 26%
Cancer, Lipids, and Metabolism
0.94
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