Genotypic diversity and molecular characterization of DENV-2 in a Peruvian endemic region from 2016 to 2022: displacement of American/Asian genotype
Similarly, our findings showed that every studied outbreak was characterized by novel autochthonous variants of the Am/As genotype and by an imported variant of the cosmopolitan genotype; this demonstrates a temporal distribution of intraserotypic variability that indicates the displacement of the Am/As genotype around 2021 and the establishment of the cosmopolitan genotype. The need for ongoing genetic or genomic surveillance of the cosmopolitan virus arises in order to understand its distribution and diversification patterns in Peru.
Authors
- Yordi Tarazona-Castro (ORCID: https://orcid.org/0000-0003-0740-4502)
- Jorge Bazán-Mayra (ORCID: https://orcid.org/0000-0002-9984-8196)
- Egma Mayta-Huatuco (ORCID: https://orcid.org/0000-0001-8471-1675)
- Wilmer Silva-Caso (ORCID: https://orcid.org/0000-0003-1086-8084)
- Víctor Zavaleta-Gavidia (ORCID: https://orcid.org/0000-0003-1760-4241)
- Luís J. del Valle (ORCID: https://orcid.org/0000-0001-9916-1741)
- Ronald Aquino-Ortega (ORCID: https://orcid.org/0000-0002-9100-8547)
- Miguel Ángel Aguilar-Luis (ORCID: https://orcid.org/0000-0001-7023-3190)
- Juana del Valle-Mendoza (ORCID: https://orcid.org/0000-0002-6011-5040)
- Hugh Watson
Institutions
- Peruvian University of Applied Sciences (PE)
- National University of Cajamarca (PE)
- National University of San Marcos (PE)
- Universitat Politècnica de Catalunya (ES)
- Evotec (United States) (US)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-04-28
- DOI
- https://doi.org/10.3389/fmicb.2025.1558761
- Citations
- 4
- Primary Topic
- Mosquito-borne diseases and control
- Type
- article
- Field-Weighted Citation Impact
- 7.51