Skin transcriptomic and selection signature analyses identify ASIP as a key gene in cattle coat color determination
Based on the skin transcriptomic and genomic analyses, we found that <i>ASIP</i> was significantly differential expressed between black and brown cattle breeds and under strong positive selection. These findings provide valuable insights into the genetic basis of coat color variation in cattle and highlight the ASIP gene as a critical determinant of this trait.
Authors
- Junjie Wu (ORCID: https://orcid.org/0000-0002-4000-7026)
- Yuanfeng Zhao (ORCID: https://orcid.org/0000-0002-3849-4048)
- Yanli Lv
- Hua Wang (ORCID: https://orcid.org/0000-0002-4761-3862)
- Longxin Xu (ORCID: https://orcid.org/0000-0002-4231-1662)
- Jipan Zhang (ORCID: https://orcid.org/0000-0002-3562-4118)
- Xin Wang (ORCID: https://orcid.org/0000-0002-7762-1935)
- Mengmeng Ni
- Wenzhang Zhou (ORCID: https://orcid.org/0009-0003-1434-0874)
- Di Zhou (ORCID: https://orcid.org/0000-0002-9248-7703)
- Kai-Kai Zhang
Institutions
- Southwest University (CN)
- Guizhou University (CN)
- Guizhou Academy of Agricultural Sciences (CN)
- Poultry Research Institute (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2025-04-28
- DOI
- https://doi.org/10.3389/fgene.2025.1577647
- Citations
- 2
- Primary Topic
- melanin and skin pigmentation
- Type
- article
- Field-Weighted Citation Impact
- 2.30
Funders
- Guizhou Academy of Agricultural Sciences