Reduced finger tapping speed in patients with schizophrenia and psychomotor slowing: an exploratory fMRI study
In both task complexity and movement onset factor levels, all the groups activated sensorimotor areas. Slowed patients had no regulation of the task-dependent cerebellar involvement while showing insufficient deactivation of the SPL, pointing to altered recruitment of neural resources in response to motor demands in schizophrenia especially when associated with psychomotor slowing.
Authors
- Stewart A. Shankman (ORCID: https://orcid.org/0000-0002-8097-4483)
- Sebastian Walther (ORCID: https://orcid.org/0000-0003-4026-3561)
- Jessica A. Bernard (ORCID: https://orcid.org/0000-0001-7697-3675)
- Niluja Nadesalingam (ORCID: https://orcid.org/0000-0002-5221-5148)
- Alexandra Kyrou
- Florian Wüthrich (ORCID: https://orcid.org/0000-0001-6007-8668)
- Stéphanie Lefebvre (ORCID: https://orcid.org/0000-0003-4833-2197)
- Vijay Anand Mittal (ORCID: https://orcid.org/0000-0001-9017-5119)
- Melanie G. Nuoffer (ORCID: https://orcid.org/0000-0003-4146-4410)
- Marc O Zindel
Institutions
- Northwestern University (US)
- University of Bern (CH)
- Texas College (US)
- Universitätsklinikum Würzburg (DE)
- Hologic (Germany) (DE)
- Texas A&M University (US)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2025-04-28
- DOI
- https://doi.org/10.3389/fpsyt.2025.1539112
- Citations
- 1
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.47