Retrospective clinical and molecular characterisation of patients with penile intraepithelial neoplasia
We identified seven overexpressed genes in patients with PeIN recurrence. Some of these transcripts were previously reported to be involved in invasive penile cancer. These findings provide molecular evidence, that PeIN is a precursor lesion with a correlation to invasive penile cancer, and could potentially lead to new topical treatment strategies for PeIN and low-risk penile cancer.
Authors
- Sofie Laugesen (ORCID: https://orcid.org/0000-0002-3024-9347)
- Jakob Kristian Jakobsen (ORCID: https://orcid.org/0000-0003-1629-7411)
- Philippe Lamy (ORCID: https://orcid.org/0000-0003-1347-7724)
- Sara K. Elbæk (ORCID: https://orcid.org/0000-0002-0135-6995)
- Iver Nordentoft (ORCID: https://orcid.org/0000-0003-4856-4086)
- Lars Dyrskjøt (ORCID: https://orcid.org/0000-0001-7061-9851)
- Christina Stilling (ORCID: https://orcid.org/0000-0002-4356-8523)
Institutions
- Aarhus University (DK)
- Aarhus University Hospital (DK)
Publication Details
- Journal
- British Journal of Urology
- Published
- 2025-04-27
- DOI
- https://doi.org/10.1111/bju.16754
- Primary Topic
- Genital Health and Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Kræftens Bekæmpelse