Association of serum cortisol with insulin secretion and plasma aldosterone with insulin resistance in untreated type 2 diabetes: a cross-sectional study

Serum cortisol levels are associated with insulin secretion, and the PAC is associated with insulin resistance in patients with untreated type 2 diabetes. These findings suggest that aldosterone blockade may represent a potential therapeutic approach for reducing insulin resistance in patients with type 2 diabetes.

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Publication Details

Journal
Diabetology & Metabolic Syndrome
Published
2025-04-28
DOI
https://doi.org/10.1186/s13098-025-01706-8
Citations
1
Primary Topic
Hormonal Regulation and Hypertension
Type
article
Field-Weighted Citation Impact
1.29
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Association of serum cortisol with insulin secretion and plasma aldosterone with insulin resistance in untreated type 2 diabetes: a cross-sectional study

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article

Association of serum cortisol with insulin secretion and plasma aldosterone with insulin resistance in untreated type 2 diabetes: a cross-sectional study

Naoyuki Kawagoe, Masahiro Ohira, Hajime Ueshiba, Yuko Kondou, Chisato Kameyama, M. Igarashi
article en
1 citations

Abstract

Serum cortisol levels are associated with insulin secretion, and the PAC is associated with insulin resistance in patients with untreated type 2 diabetes. These findings suggest that aldosterone blockade may represent a potential therapeutic approach for reducing insulin resistance in patients with type 2 diabetes.

Diabetology & Metabolic SyndromeVol. 17(1)
Toho University (JP), Toho University Ohashi Medical Center (JP)
Good health and well-being
Openalex Percentile: Top 20%
Hormonal Regulation and Hypertension
1.29
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