Vaccination with inactivated SARS-CoV-2 vaccine TURKOVAC induces durable humoral and cellular immune responses up to 8 months
TURKOVAC vaccination induces durable immune responses, with spike-specific B cells persisting up to 8 months and T cell responses peaking at 4 months before declining. These findings suggest that TURKOVAC contributes to long-term immune protection against SARS-CoV-2.
Authors
- Hazel Yetişkin (ORCID: https://orcid.org/0000-0003-0813-791X)
- Gökmen Zararsız (ORCID: https://orcid.org/0000-0001-5801-1835)
- Ahmet Eken (ORCID: https://orcid.org/0000-0002-5816-0686)
- Adnan Bayram (ORCID: https://orcid.org/0000-0002-6700-8301)
- Muhammet Ali Uygut (ORCID: https://orcid.org/0000-0002-8794-341X)
- Seçil Yılmaz (ORCID: https://orcid.org/0000-0001-9381-828X)
- Serra İlayda Yerlitaş (ORCID: https://orcid.org/0000-0003-2830-3006)
- Medine Doğan Sarıkaya (ORCID: https://orcid.org/0000-0003-0435-6066)
- Aykut Özdarendeli (ORCID: https://orcid.org/0000-0002-6950-8545)
- Burcu Şen Bağcı (ORCID: https://orcid.org/0000-0002-4526-5198)
- Ahmet İnal (ORCID: https://orcid.org/0000-0002-5917-3729)
- Shaikh Terkıs Islam Pavel (ORCID: https://orcid.org/0000-0002-7178-0943)
- Ateş Kara (ORCID: https://orcid.org/0000-0002-1654-3232)
- Gamze Kalın Ünüvar (ORCID: https://orcid.org/0000-0001-7209-8826)
- Zafer Sezer (ORCID: https://orcid.org/0000-0003-4858-3906)
- Şerife Erdem (ORCID: https://orcid.org/0000-0002-2255-1685)
- B. S. Kaplan (ORCID: https://orcid.org/0000-0002-2029-6270)
- Nuri Çakır (ORCID: https://orcid.org/0000-0002-9935-7397)
Institutions
- Hacettepe University Hospital (TR)
- Erciyes University (TR)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-04-28
- DOI
- https://doi.org/10.3389/fmed.2025.1524393
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Erciyes Üniversitesi