Risk factors for the progression from pulmonary tuberculosis to spinal tuberculosis: a logistic regression analysis
This study highlights critical risk factors for the progression from PTB to STB, particularly the NRS-2002 score, recurrent PTB, and socioeconomic status (living in relative poverty). The NRS-2002 score was identified as the most significant predictor, demonstrating a strong dose-response relationship with disease progression. Clinically, early identification of patients with elevated NRS-2002 scores, alongside timely nutritional interventions and efforts to alleviate poverty, can significantly reduce the risk of STB development. These findings can inform clinical decision-making, enhance early intervention strategies, and guide public health policies aimed at preventing STB, particularly in high-risk populations.
Authors
- Qinfu Liu (ORCID: https://orcid.org/0000-0001-8992-7571)
- Yajing Su
- Jia Chen (ORCID: https://orcid.org/0000-0001-5924-8674)
- Min Su (ORCID: https://orcid.org/0000-0003-3589-9573)
- Xiaolei Chen (ORCID: https://orcid.org/0000-0003-1908-8789)
- Xue Lin (ORCID: https://orcid.org/0000-0001-7934-5682)
- Chen Zhang (ORCID: https://orcid.org/0000-0001-6304-9360)
- Yiqiang Yang
- Zhirong Chen (ORCID: https://orcid.org/0009-0001-7039-7707)
- Lingyun Shao (ORCID: https://orcid.org/0000-0001-8514-1029)
- Zhìqiáng Wú (ORCID: https://orcid.org/0000-0003-1139-3260)
- Di Xue
Institutions
- Fujian Medical University (CN)
- Ningxia University (CN)
- Quzhou City People's Hospital (CN)
- The 180th Hospital of PLA (CN)
- First Affiliated Hospital of Fujian Medical University (CN)
- Ningxia Seismological Bureau (CN)
- Ningxia Medical University (CN)
- Ningxia Medical University General Hospital (CN)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2025-04-28
- DOI
- https://doi.org/10.1186/s13018-025-05848-3
- Citations
- 2
- Primary Topic
- Infectious Diseases and Tuberculosis
- Type
- article
- Field-Weighted Citation Impact
- 4.01
Funders
- National Natural Science Foundation of China
- Key Research and Development Program of Ningxia