Investigation of the interplay of PCSK9, cardiac dynamics, oxidative stress in coronary artery disease: case-control study

While PCSK9's role in MI through LDL-C is well known, its impact on inflammation and oxidative stress may also be important, even when LDL-C and PCSK9 levels are normal. Additionally, ox-LDL and EF% are better indicators of CAB > 50% than hs-cTnI.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2025-04-28
DOI
https://doi.org/10.3389/fendo.2025.1494438
Primary Topic
Lipoproteins and Cardiovascular Health
Type
article
Field-Weighted Citation Impact
0.00

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article

Investigation of the interplay of PCSK9, cardiac dynamics, oxidative stress in coronary artery disease: case-control study

A. Lafta, Hamidreza Shiri, Nahid Einollahi, Monireh Rahimkhani et al.
Frontiers in Endocrinology
Lipoproteins and Cardiovascular Health
article

Investigation of the interplay of PCSK9, cardiac dynamics, oxidative stress in coronary artery disease: case-control study

A. Lafta, Hamidreza Shiri, Nahid Einollahi, Monireh Rahimkhani, Mahsa Iraji, Amin Karimpour, Mahboobe Sattari
article en

Abstract

While PCSK9's role in MI through LDL-C is well known, its impact on inflammation and oxidative stress may also be important, even when LDL-C and PCSK9 levels are normal. Additionally, ox-LDL and EF% are better indicators of CAB > 50% than hs-cTnI.

Frontiers in EndocrinologyVol. 16
Tehran University of Medical Sciences (IR)
Tehran University of Medical Sciences and Health Services
Openalex Percentile: Top 85%
Lipoproteins and Cardiovascular Health
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