Teplizumab: a promising intervention for delaying type 1 diabetes progression

Type 1 diabetes (T1D) arises from an autoimmune attack on pancreatic beta cells, leading to a reliance on external insulin to maintain glucose levels. In recent years, research has increasingly focused on preventive strategies for individuals at high risk. A promising new intervention in this field is Teplizumab, the first approved disease-modifying therapy for T1D. Teplizumab is designed to delay progression to stage 3 T1D in adults and children aged 8 years and older who are diagnosed with stage 2 T1D.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2025-04-28
DOI
https://doi.org/10.3389/fendo.2025.1533748
Citations
5
Primary Topic
Diabetes and associated disorders
Type
article
Field-Weighted Citation Impact
9.09

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article

Teplizumab: a promising intervention for delaying type 1 diabetes progression

Muhammad Rizwan Saleem, Muhammad Talha Khan
5 citations
Frontiers in Endocrinology
Diabetes and associated disorders
9.09
article

Teplizumab: a promising intervention for delaying type 1 diabetes progression

Muhammad Rizwan Saleem, Muhammad Talha Khan
article en
5 citations

Abstract

Type 1 diabetes (T1D) arises from an autoimmune attack on pancreatic beta cells, leading to a reliance on external insulin to maintain glucose levels. In recent years, research has increasingly focused on preventive strategies for individuals at high risk. A promising new intervention in this field is Teplizumab, the first approved disease-modifying therapy for T1D. Teplizumab is designed to delay progression to stage 3 T1D in adults and children aged 8 years and older who are diagnosed with stage 2 T1D.

Frontiers in EndocrinologyVol. 16
Dow University of Health Sciences (PK)
Servier
Good health and well-being
Openalex Percentile: Top 2%
Diabetes and associated disorders
9.09
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