Tight Junction Modulatory Fusion Peptide (ADT-6) Enhances GFP Protein Permeability through the Paracellular Pathway in Caco-2 Cell Lines: An In-Vitro Study
This study demonstrates the potential of ADT-6 to deliver proteins from the paracellular route, enhance the bioavailability of pharmaceutical drugs by altering cell-cell interactions, and provide new opportunities for oral drug delivery strategies.
Authors
- Seyedeh‐Nafiseh Hassani (ORCID: https://orcid.org/0000-0001-5047-8406)
- Ghasem Bagherpour (ORCID: https://orcid.org/0000-0002-5932-5884)
- Rahim Jafari (ORCID: https://orcid.org/0000-0003-0931-835X)
- Keyvan Nedaei
Institutions
- Zanjan University of Medical Sciences (IR)
- Biotechnology Research Center (IR)
Publication Details
- Journal
- Reports of Biochemistry and Molecular Biology
- Published
- 2024-11-01
- DOI
- https://doi.org/10.61186/rbmb.13.3.349
- Primary Topic
- Barrier Structure and Function Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Zanjan University of Medical Sciences
- University of Zanjan